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Proteins Evolve Differentially in Saccharomyces

Blogging about Peer-Reviewed ResearchPerhaps not a surprise to anyone that has dabbled in evolutionary analysis of proteins, Kawahara and Imanishi (BMC Evolutionary Biology 2007) confirm that not every protein evolves via a molecular clock in Saccharomyces
sensu scricto. Using everyone’s favorite evolutionary tool, PAML, the authors identify protein lineages via a whole genome scan that evolve relatively slow [...]

maple syrup fungus

Kathie Hodge has a nice description with cool photos of a fungus growing in maple syrup. I guess I better make sure our syrup is in the [...]

Fungal Genetics 2007 details

I’m including a recapping as many of the talks as I remember. There were 6 concurrent sessions each afternoon so you have to miss a lot of talks. The conference was bursting at the seams as it was- at least 140 people had to be turned away beyond the 750 who attended.

If there was any theme in the conference it was “Hey we are all using these genome [...]

Fungal Genetics 2007 summary

A Fungal Genetics 2007 summary.
Wow. What a meeting! I am still exhausted and not just because of the very late Saturday night dancing at the close of the conference. I will just say anyone who thinks scientists are boring people should witness the passion researchers have for their science and in sharing it with other people. [...]

Hello, do I know you?

Blogging about Peer-Reviewed ResearchSelf and non-self recognition is important for fungi when hyphae interact fuse if they should compartmentalize and undergo apoptosis to kill the heterokaryoton or exchange nutrients. This process is part of cell defense and to limit to the movement of mycoviruses.

A paper in PLOS ONE describes the Genesis of Fungal Non-Self Repertoire. [...]

At Asilomar

We’re at Asilomar mtg for Fungal Genetics 2007. We’ll try and blog a bit about the interesting talks and data. I’m curious how many fungal geneticists are in fact reading blogs like these and if this medium will work for idea [...]

Genome resources for Candida species

The Candida clade of Hemiascomycete fungi have received much attention from funding bodies so that many genomic and experimental resources are available address questions of pathogenecity and industrial applications of these species.

The Candida genus

Traditionally, species of yeasts that were thought to be asexual were given the genus name Candida. This has lead to Candida being a sort of taxonomic rubbish [...]

Yeast resequencing data updated

Image from http://www.bath.ac.uk/bio-sci/wheals2.htmThe Saccharomyces Genome Resequencing Project has completed ” ABI sequencing of 32 S. cerevisiae strains and 27 S. paradoxus strains to a depth of between 1x and 3x”. This is in collaboration with Ed Louis’ group who have been working on number of really interesting fungal [...]

SGD community annotation

The Saccharomyces Genome Database has deployed a wiki for gene annotation from the community.  This should be an interesting experiment in how information can flow from the community into these [...]

Yeast keeps to itself

Cliff Zeyl and Sally Otto present a nice review on research from the Kruglyak lab regarding evidence that Saccharomyces is primarily a selfer in nature as it outbreeds very infrequently (once in 50,000 generations). The implications of this work has relevance on the importance of sexual reproduction and recombination in natural [...]