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Candida White-Opaque switching

Blogging on Peer-Reviewed ResearchA paper in PLoS Biology from Sandy Johnson’s lab entitled “Interlocking Transcriptional Feedback Loops Control White-Opaque Switching in Candida albicans” discusses phenotype switching in the human pathogenic fungus Candida albicans. Why is the [...]

I hate it when I lose chromosomes

Blogging on Peer-Reviewed ResearchA paper on “Effects of Aneuploidy on Cellular Division in Haploid Yeast” describes what must be a very stressful situation for a cell, when it loses or gains a [...]

Mucor circinelloides genome update

I recently heard through the grapevine that the Mucor ircinelloides genome 4X assembly was completed by JGI and a BLAST server is available if you contact the authors. Mucorales (previously Zygomycota which is not monophyletic) includes previously sequenced Rhizopus oryzae and Phycomyces blakesleeanus which we’ve blogged about before.

Mucor is model system for the Zygos/Mucorales as it can be

Yeast resequencing update

Ed Louis at Nottingham sent out an email today outlining plans for publishing analyses of the Saccharomyces Genome Resequencing Project.  They are in process of analyzing the data and ask that people respect their use of the data, but also invite collaborations and companion [...]

Contact your represenative: Vote in the Senate on NIH Funding

This was sent along from the GSA. It is important to contact your represenative about the Vote in the Senate on NIH Funding.
The Senate is expected to vote on the Fiscal Year 2008 Labor, Health and Human Services and Education (L-HHS) appropriations bill the week of October [...]

Exploring CUG codon evolution in Candida

Reverting CUG tRNA from derived change coding for serine back to leucine (standard code) has profound effect on [...]

Bay Area Seminar(s): Jonathan Eisen

For those within reach of Bay Area, Jonanthan Eisen (who recently posted about 3-day Biology and Mathematics in the Bay Area meeting) will be presenting at Bay Area BioSystematists meeting on Oct 16. [...]

Yes, Ecology can improve Genomics

Blogging on Peer-Reviewed ResearchFew organisms are as well understood at the genetic level as Saccharomyces cerevisiae. Given that there are more yeast geneticists than yeast genes and exemplary resources for the community (largely a result of their size), this comes as no surprise. [...]

Next gen sequencing technology

Nature has an overview of what goes in and out of next generation sequencers with an interview with a smiling Chad Nusbaum from the Broad Institute. Most of these have been out and about for a while, but it seems that the hayride/bandwagon is starting to pick up more steam as GT’s Genome Scan has several posts about sequencing referencing J. Craig V,

Little Coprinus mushroom pictures

Coprinus cinereus (renamed Coprinopsis cinerea) growing in the lab. The genome was sequenced, assembled into chromosomes, and annotated and we are working on the final analysis of it to describe some of the interesting biology about this little Coprophilic fungus. I’m excited to put up a few of my pictures of the tiny mushrooms growing in the lab (although others [...]