The Stagonospra nodorum (teleomorph Phaeosphaeria nodorum) genome is now published in Plant Cell, “Sequencing and EST Analysis of the Wheat Pathogen Stagonospora nodorum”. The paper describes the sequencing and analysis of this Dothideomycete fungus. The analyses included identifying genes likely involved in pathogenecity such as PKS and NRPS genes and enabled the discovery of new genes like ToxA.
A couple of surprising findings:
- The genome was found to have both Class 1 and Class 2 Hydrophobin genes. Class 2 are normally restricted to basidiomycetes.
- Secreted proteins were not clustered in the genome
- There appeared to be more secreted proteins shared with the plant pathogen M. grisea and N. crassa indicating some even though they are equidistant to S. nodorum although this analysis would need more sampled genomes of saprotrophic and biotrophic fungi to really support this hypothesis.
The paper has a few more observations about genome organization and synteny conservation, EST analyses of the fungus during infection, and a potential role for horizontal transfer among fungi to exchange pathogenic genes that make it worth taking a look.