A nice series of comparative genomics articles have been published in the last few weeks. The pace of genome sequencing has accelerated to the point that we have lots of sequencing projects coming from individual labs and small consortia not necessarily from genome centers. We are seeing a preview of what next (2nd) generation [...]
|
|||||
Blog under the
Creative Commons Attribution 3.0 License
|
There is an article in Wine Spectator (Seen on the JGI feed) on sequencing the wine spoilage yeast bruxellensis (correct name is now Dekkera bruxellensis) which adds the not-so-excellent taste of “sweaty horse” to wines. There is already some survey sequencing done by Ken Wolfe and Jurge Piskur’s groups so a full genome sequencing project will [...] Too much on my plate as of late, so I’m woefully behind on posting much on interesting papers or news. Here’s a short list of links and papers that are worth a look though. “Evolution of pathogenicity and sexual reproduction in eight Candida genomes” published (Nature) In a letter to the editor to the journal Nature, regarding the recently discovered/induced sexual stage in Aspergillus fumigatus, David Hawksworth argues that using the separate names for sexual (teleomorph) and asexual (anamorph) stages is confusing and unnecessary in this context. The name Neosartorya fumigata is given to the sexual stage which was produced from two [...] Take a look at this post by Larry Moran on Takao Kasuga’s paper on phylogenetic distribution of genes in N. crassa genome. [...]
The JGI in collaboration with our lab at Berkeley have released the Neurospora tetrasperma (mat A) and N. discreta (mat A) genome sequences and annotation after about two years of work. These are two closely related species to the well studied laboratory workhorse Neurospora crassa. The N.tetrasperma assembly (8X) has an N50 of 976kb and is [...] A recent paper in MBE presents evidence that the Taphrinomycota (containing S. pombe and Pneumocystis) are in fact a monophyletic group. This is considered an early branch in the Ascomycota with the Pezizomycotina (filamentous ascomycete fungi like Neurospora and Aspergillus) and Saccharomycotina (fungi mainly with yeast forms including Candida and Saccharomyces). The monophyly of Taphrinomyoctina fungi is something that has been fairly accepted but there are a few publications reporting conflicting evidence in some sets gene trees. This conflict is most likely due to Long Branch Attraction (LBA) and the Philippe lab has long worked on this problem of LBA working to develop tools like PhyloBayes that attempt to correct for LBA with a parameter rich model and using lots of data (like whole [...] A manuscript at Nature AOP details the success of the Dyer lab and collaborators in encouraging [[Aspergillus fumigatus]] to complete the sexual cycle under observable (e.g. laboratory) conditions. The authors are the teleomorph (sexual or perfect) stage [[Neosartorya fumigata]] for a fungus that had been previously only had an observed anamorphic stage. A. fumigatus can reproduce asexually forming structures called [[conidiophores]] which produce asexual spores called [[conidiospores]] (or mitospores as they are produced via mitosis) define the anamorph or imperfect stage, but no sexual structures such as [[cleistothecia]] that produce the packaged sexual products as [[ascospores]]. See a presentation by David Geiser (archived at the Aspergillus website) for more detail on some of the morphological and phylogenetic characters that unify the group of Eurotiales [...] |
||||
|
Copyright © 2010 The Hyphal Tip - All Rights Reserved |
|||||
Shepard Fairley has gotten alot of notice lately for his Obama art that has been replicated pretty much everywhere. In homage to his earlier street art we’ll discuss the growing Aspergillus genome [...]