By Jason Stajich, on September 14th, 2009
A nice series of comparative genomics articles have been published in the last few weeks. The pace of genome sequencing has accelerated to the point that we have lots of sequencing projects coming from individual labs and small consortia not necessarily from genome centers. We are seeing a preview of what next (2nd) generation sequencing [...]
By Jason Stajich, on May 26th, 2009
Too much on my plate as of late, so I’m woefully behind on posting much on interesting papers or news. Here’s a short list of links and papers that are worth a look though.
“Evolution of pathogenicity and sexual reproduction in eight Candida genomes” published (Nature)
NYT Science article sort of summarizing the good, bad, and ugly of fungi and [...]
By Jason Stajich, on October 31st, 2007
A paper in PLoS Biology from Sandy Johnson’s lab entitled “Interlocking Transcriptional Feedback Loops Control White-Opaque Switching in Candida albicans” discusses phenotype switching in the human pathogenic fungus Candida albicans. Why is the important?
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By Jason Stajich, on October 9th, 2007
Reverting CUG tRNA from derived change coding for serine back to leucine (standard code) has profound effect on organism. [...]
By Jason Stajich, on September 18th, 2007
A recent paper “Targeted gene deletion in Candida parapsilosis demonstrates the role of secreted lipase in virulence”, from the Nosanchuk lab at Yeshiva University, shows the role of secreted lipases in virulence of this pathogen. [...]
By Jason Stajich, on March 18th, 2007
The Candida clade of Hemiascomycete fungi have received much attention from funding bodies so that many genomic and experimental resources are available address questions of pathogenecity and industrial applications of these species.
The Candida genus
Traditionally, species of yeasts that were thought to be asexual were given the genus name Candida. This has lead to Candida being a sort of taxonomic rubbish bin. [...]