An article about the Fungal Genetics Stock Center written by the curators provides some insight into the 50 year history of this resource. It is a great summary of how the stock center has grown over the years and demonstrates how it is an essential aspect of how research on filamentous fungi is possible. The FGSC [...]
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I spy a picture of Neurospora growing on the cover of Genetics this month. The cover highlights the results from the work of the lab of Luis Corrochano who works on light regulation in a variety of systems like Neurospora and Phycomyces. This work describes their work on the fluffy gene which regulates conidiation (production of conidia or asexual [...] Too much on my plate as of late, so I’m woefully behind on posting much on interesting papers or news. Here’s a short list of links and papers that are worth a look though. “Evolution of pathogenicity and sexual reproduction in eight Candida genomes” published (Nature) Take a look at this post by Larry Moran on Takao Kasuga’s paper on phylogenetic distribution of genes in N. crassa genome. [...] The JGI in collaboration with our lab at Berkeley have released the Neurospora tetrasperma (mat A) and N. discreta (mat A) genome sequences and annotation after about two years of work. These are two closely related species to the well studied laboratory workhorse Neurospora crassa. The N.tetrasperma assembly (8X) has an N50 of 976kb and is highly [...] This is a research blog so I though I’d post some quick numbers we are seeing for de novo assembly of the [[Neurospora crassa]] genome using Velvet. The genome of N.crassa is about 40Mb and sequencing of several flow cells using Solexa/Illumina technology to see what kind of de novo reconstruction we’d get. [...]
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Another asexual species of fungi also has evidence for the meiosis-specific process of Repeat Induced Point-mutations (RIP). [...] DuPont/Pioneer Hi-Bred has donated the genome sequence of the Sordariomycete Colletotrichum graminicola into the public domain by depositing the sequence in GenBank. The FGI through the Broad Institute are also sequencing a strain of C. graminicola (teleomorph Glomerella graminicola) [...] |
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The [[Trichoderma reesei]] genome paper was recently published in Nature Biotechnology from Diego Martinez at [[LANL]] with collaborators at [[JGI]], [[LBNL]], and others. This fungus was chosen for sequencing because it was found on canvas tents eating the cotton material suggesting it may be a good candidate for degrading cellulose plant material as part of cellulosic ethanol production.