By Jason Stajich, on May 6th, 2008
The transcriptional landscape of yeast has been (further) defined with [[Solexa]] sequencing in a method deemed “RNA-Seq”, but what I would call “deep EST sequencing”. This approach for transcriptional profiling by sequencing alone is sure to be used by many labs looking for lower and more complete ways to describe and quantitate the full population of transcripts in an [...]
By sharpton, on October 5th, 2007
Few organisms are as well understood at the genetic level as Saccharomyces cerevisiae. Given that there are more yeast geneticists than yeast genes and exemplary resources for the community (largely a result of their size), this comes as no surprise. [...]
By Jason Stajich, on May 20th, 2007
From Genetics this week a review discusses Why are there still 1000 Uncharacterized Yeast genes? Poor Yeast – so many more genes have no known function, while S. pombe has nearly 100% coverage in functional annotation. I’ll also point out that the 1000 genes refers to protein-coding genes, not ncRNA genes which may mean that there is alot more that is [...]
By Jason Stajich, on May 15th, 2007
Lots of papers in Mycologia (subscription required) this month of different groups analyzing the fine-scale relationships of many different fungal clades using the loads of sequences that were generated as part of the Fungal Tree of Life [...]
By Jason Stajich, on May 13th, 2007
I read this blurb in the New Scientist about a PNAS paper (subscription required for next 6 months) on how hive beetles (Aethina tumida) are able to infest bee hives by throwing off the bees because they are producing isopentyl acetate which is thought to be produced and used by bees to signal an alarm. [...]
By Jason Stajich, on March 7th, 2007
Cliff Zeyl and Sally Otto present a nice review on research from the Kruglyak lab regarding evidence that Saccharomyces is primarily a selfer in nature as it outbreeds very infrequently (once in 50,000 generations). The implications of this work has relevance on the importance of sexual reproduction and recombination in natural [...]