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A cacophony of comparative genomics papers

A nice series of comparative genomics articles have been published in the last few weeks. The pace of genome sequencing has accelerated to the point that we have lots of sequencing projects coming from individual labs and small consortia not necessarily from genome centers. We are seeing a preview of what next (2nd) generation [...]

Mucor circinelloides genome and annotation available

The Mucormycotina (formerly Zygomycota) fungus Mucor circinelloides Genome Portal is now publicly available at http://genome.jgi-psf.org/Mucci1/Mucci1.home.html.

If you are planning to attend the Fungal Conference in Asilomar, there will be a JGI Workshop on March 19, 2009 at noon in Chapel to show how to use the manual curation tools.

Escaping the dung pile quickly: Speedy Pilobolus spores

Sporangiophore discharge in the fungus Pilobolus kleinii captured with high speed video. In a paper appearing today in PLoS One, “The Fastest Flights in Nature: High-Speed Spore Discharge Mechanisms among Fungi” Nicholas Money and colleagues including 6 undergraduates and 3 graduate students, have measured the speed of flight of spores discharging from several Ascomycete and Zygomycete dung [...]

Papers on our desk

A quick post of some recent comparative genomics papers on our desk that are worth a look.

Khaldi N, Wolfe KH (2008) Elusive Origins of the Extra Genes in Aspergillus oryzae. PLoS ONE 3(8): e3036. doi:10.1371/journal.pone.0003036. This was a cool but somewhat controversal [...]

Will a zygomycete help solve our energy woes?

I found the headline today, “Biofuels: Fungus Use Improves Corn-to-ethanol Process” and I was curious to find out what fungus they were talking about in the article. It turns out that researchers at Iowa State University found that Rhizopus microsporus is able to grow off part of the leftovers of ethanol production called thin stillage. [...]

Some links

ResearchBlogging.org

I’ve been too busy to post much these last few days, but here are a few links to some papers I found interesting in my recent browsing.

Sex in fungi: MAT locus cloned from a Zygomycete

Blogging on Peer-Reviewed ResearchOn the cover of this week’s Nature is a picture of Phycomyces blakesleeanus Nature Coverhighlighting the discovery of the MAT locus in this Zygomycete fungus from Alex Idnurm and Joe Heitman and colleagues. While it was previously known that Zygomycetes (the Orange lineage represented by R. oryzae in the tree below) mate, the specific locus has until now, never been discovered. The authors in this study identified the MAT locus through a sequence search looking for HMG-box genes knowing that these are found the Mating Type locus in Basidiomycetes and Ascomycetes. They confirmed the identity through a through set of experiments that included PCR, sequencing and crosses of (+) and (-) strains of P. blakesleeanus, and Southern [...]

Mucor circinelloides genome update

I recently heard through the grapevine that the Mucor ircinelloides genome 4X assembly was completed by JGI and a BLAST server is available if you contact the authors. Mucorales (previously Zygomycota which is not monophyletic) includes previously sequenced Rhizopus oryzae and Phycomyces blakesleeanus which we’ve blogged about before.

Mucor is model system for the Zygos/Mucorales as it can be

Fungal tree of life papers

Lots of papers in Mycologia (subscription required) this month of different groups analyzing the fine-scale relationships of many different fungal clades using the loads of sequences that were generated as part of the Fungal Tree of Life [...]

Fungal Genetics 2007 details

I’m including a recapping as many of the talks as I remember. There were 6 concurrent sessions each afternoon so you have to miss a lot of talks. The conference was bursting at the seams as it was- at least 140 people had to be turned away beyond the 750 who attended.

If there was any theme in the conference it was “Hey we are all using these genome [...]