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Too much on my plate as of late, so I’m woefully behind on posting much on interesting papers or news. Here’s a short list of links and papers that are worth a look though. “Evolution of pathogenicity and sexual reproduction in eight Candida genomes” published (Nature)
This is a research blog so I though I’d post some quick numbers we are seeing for de novo assembly of the [[Neurospora crassa]] genome using Velvet. The genome of N.crassa is about 40Mb and sequencing of several flow cells using Solexa/Illumina technology to see what kind of de novo reconstruction we’d get. [...]
I’m not at AGBT, but Jonathan and Anthony both have coverage of Pacific Biosciences’s new sequencing technology that uses detection of DNA polymerase activity to determine sequence. I believe some of the details are in the paper “Selective aluminum passivation for targeted immobilization of single DNA polymerase molecules in zero-mode waveguide [...]
While many strains of S. cerevisiae are being sequenced, a single strain, YJM789, isolated from the lung of an AIDS patient was sequenced a few years ago at Stanford and published this summer. The genome was described in a paper entitled “Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789″. Ed Louis at Nottingham sent out an email today outlining plans for publishing analyses of the Saccharomyces Genome Resequencing Project. They are in process of analyzing the data and ask that people respect their use of the data, but also invite collaborations and companion [...] Nature has an overview of what goes in and out of next generation sequencers with an interview with a smiling Chad Nusbaum from the Broad Institute. Most of these have been out and about for a while, but it seems that the hayride/bandwagon is starting to pick up more steam as GT’s Genome Scan has several posts about sequencing referencing J. Craig V,
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