An article in PLoS Pathogens by Morris et al describe a hypothesis about the evolution and origins of plant pathogens applying the parallel theories to the emergence of medically relevant pathogens. The authors highlight the importance of understanding the evolution of organisms in the context of emerging pathogens like Puccinia Ug99 for our ability [...]
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A new and improved annotation of Cryptococcus neoformans var grubii strain H99 (serotype A) has been made available in GenBank and the Broad Institute website. This update is collaboration between several groups providing data and analyses and the annotation team at Broad’s gene calling [...] A manuscript at Nature AOP details the success of the Dyer lab and collaborators in encouraging [[Aspergillus fumigatus]] to complete the sexual cycle under observable (e.g. laboratory) conditions. The authors are the teleomorph (sexual or perfect) stage [[Neosartorya fumigata]] for a fungus that had been previously only had an observed anamorphic stage. A. fumigatus can reproduce asexually forming structures called [[conidiophores]] which produce asexual spores called [[conidiospores]] (or mitospores as they are produced via mitosis) define the anamorph or imperfect stage, but no sexual structures such as [[cleistothecia]] that produce the packaged sexual products as [[ascospores]]. See a presentation by David Geiser (archived at the Aspergillus website) for more detail on some of the morphological and phylogenetic characters that unify the group of Eurotiales [...] Here’s a fungal infection you don’t hear much about. One of the fungi we work on, a model for mushroom development as it can be fruited in the lab is Coprinopsis cinerea (previously named Coprinus cinereus). C. cinerea is a saprobric coprophillic fungus so it is usually found on dung. Although rare in human infections there are a few reports in immunocopromised patients. [...]
While many strains of S. cerevisiae are being sequenced, a single strain, YJM789, isolated from the lung of an AIDS patient was sequenced a few years ago at Stanford and published this summer. The genome was described in a paper entitled “Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789″.
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