Tag Archives: antifungal

Amphibian skin bacteria shown to fight off Batrachochytrium dendrobatidis.

A year ago researchers at James Madison University discovered that, Pedobacter cryoconitis, a bacteria first found on the skin of red backed salamanders, was found to prevent the growth of the chytrid B. dendrobatidis, which is currently decimating frog populations.

(Mountain Yellow-Legged Frog from wikipedia)

The newest research on the subject is being presented this year at ASM by Brianna Lam who worked with other biologists from both San Francisco State University and JMU.

Lam’s research indicates that adding pedobacter to the skin of mountain yellow-legged frogs would lessen the effects of Batrachochytrium dendrobatidis (Bd), a lethal skin pathogen that is threatening remaining populations of the frogs in their native Sierra Nevada habitats.

Lam first conducted petri dish experiments that clearly showed the skin bacteria repelling the deadly fungus. She then tested pedobacter on live infected frogs, bathing some of them in a pedobacter solution. The frogs bathed in pedobacter solution lost less weight than those in a control group of infected frogs that were not inoculated.

In addition to the lab experiments, the JMU and SFSU researchers have studied the yellow-legged frogs in their natural habitats and discovered that some populations with the lethal skin disease survive while others go extinct. The populations that survived had significantly higher proportions of individuals with anti-Bd bacteria. The results strongly suggest that a threshold frequency of individuals need to have anti-Bd bacteria to allow a population to persist with Bd. (from Eureka alert)

The research above is really interesting and I am curious as to how the bacteria is actually killing the chytrid. The only other research I can think of where chytrids were being killed was a BBC news article that wrote about scientists bathing frogs in chloramphenicol.

Flaxseed antifungals

Blogging about Peer-Reviewed ResearchCareful eating those old noodles left in the fridge, lots of fungi probably have made a home in the starch rich environment. But can food be inoculated with some inherent antifungal properties to help it last longer. A recent paper in the Intl Journal of Food Microbiology “Fungistatic activity of flaxseed in potato dextrose agar and a fresh noodle system.” describes work to test whether flaxseed can stop fungi from growing as a potential food preservation agent. Strains of Penicillium chrysogenum, Aspergillus flavus,moldy noodles Fusarium graminearum, and other Penicillium sp isolated from moldy noodles were used in a test assay for fungistatic activity of flaxseed. Flaxseed has a whole host of health benefits that have lead to is use in many foods, cereals, and baked goods. The authors test to see what type of antifungal properties flaxseed has as well to test if it can provide a role in food preservation and be edible (or even healthy). Some other edible antifungals include spices like cinnamon, cloves, and mustard. These authors have also investigated the stability of the antifungal properties of flaxseed in another paper.