Tag Archives: mucor

Postdoc positions at Duke University & MMTP

Postdoc positions in the Heitman lab and through the Molecular Mycology Training Program at Duke University, NC State, and University of North Carolina are available as of December 1, 2014.

HeitmanImageThe Heitman lab at Duke University is seeking Postdoctoral Fellow applicants. The lab focuses on molecular determinants of development and virulence in the pathogenic basidiomycetes Cryptococcus neoformans and Cryptococcus gattii with complementary studies in both model and pathogenic fungi including Cryptococcus amylolentus, Filobasidiella depauperata, Cryptococcus heveanensis and other related basidiomycetes including Kwoniella and Malassezia species, species from the Candida pathogenic complex (C. albicans, C. lusitaniae), and the zygomycete Mucor circinelloides.

Areas of research interest include:

  • modes and impact of unisexual and sexual reproduction
  • structure, function, and evolution of the mating type locus
  • calcineurin in fungal virulence and as a novel antifungal drug target
  • comparative fungal genomics of a species cluster of human fungal pathogens
  • molecular networks that orchestrate infection of the host and development
  • RNAi based pathways operating during mitotic and sexual development and epimutational gene silencing
  • mechanisms of action of natural products and antifungal drugs

Applications should send pdfs of curriculum vitae, reprints/preprints, a statement of research accomplishments and interests, and letters of recommendation to Joseph Heitman at heitm001@duke.edu.

Myco-bio-diesel

Previously I posted on an article on making biodiesel using the fungus Gliocladium roseum. Here is a new study reporting conversion of lipids to biodiesel using the basidiomycete Cryptococcus curvatus. There has been also other progress in this area where Mucor circinelloides can also be used to produce oils suitable for biodiesel production as reported in the paper and the press release – though it is a pathogenic fungus with interesting spore size dimorphism.

Thiru M, Sankh S, & Rangaswamy V (2011). Process for biodiesel production from Cryptococcus curvatus. Bioresource technology PMID: 21930373

Mucor circinelloides genome update

I recently heard through the grapevine that the Mucor ircinelloides genome 4X assembly was completed by JGI and a BLAST server is available if you contact the authors. Mucorales (previously Zygomycota which is not monophyletic) includes previously sequenced Rhizopus oryzae and Phycomyces blakesleeanus which we’ve blogged about before.

Continue reading Mucor circinelloides genome update