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By Jason Stajich, on March 25th, 2010
I spy a picture of Neurospora growing on the cover of Genetics this month. The cover highlights the results from the work of the lab of Luis Corrochano who works on light regulation in a variety of systems like Neurospora and Phycomyces. This work describes their work on the fluffy gene which regulates conidiation (production of conidia or asexual [...]
By Jason Stajich, on March 17th, 2010
Congrats to Neurospora biologists Louise Glass and Jay Dunlap on their election to American Academy [...]
By Jason Stajich, on January 22nd, 2010
Don’t forget to register for Neurospora 2010 held at the beautiful Asilomar Conference center in Pacific Grove, CA held April 8-11, 2010. Get your filamentous fungi fix here!
Also save the date for some other important upcoming conferences you may consider attending
American Society of Microbiology, Candida and Dimorphic Fungi Meeting, March 22-26, Miami, FL, USA
Joint Genome Institute, [...]
By Jason Stajich, on April 22nd, 2009
By Jason Stajich, on June 16th, 2008
This is a research blog so I though I’d post some quick numbers we are seeing for de novo assembly of the [[Neurospora crassa]] genome using Velvet. The genome of N.crassa is about 40Mb and sequencing of several flow cells using Solexa/Illumina technology to see what kind of de novo reconstruction we’d get.
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By Jason Stajich, on May 11th, 2008
 The genome of Podospora anserina S mat+ strain was sequenced by Genoscope and CNRS and published recently in Genome Biology. The genome sequence data has been available for several years, but it is great to see a publication describing the findings. The 10X genome assembly with ~10,000 genes provides an important dataset for comparisons [...]
By Chris Villalta, on April 2nd, 2008
Interesting blog post that mentions N. crassa and RIP [...]
By Jason Stajich, on March 23rd, 2008
  A paper in Current Genetics describes the discovery of Repeat Induced Polymorphism (RIP) in two Euriotiales fungi. RIP has been extensively studied in Neurospora crassa and has been identified in other Sordariomycete fungi Magnaporthe, Fusiarium. This is not the first Aspergillus species to have RIP described as it was demonstrated in the biotech workhorse Aspergillus oryzae. However, I think this study is the first to describe RIP in a putatively asexual fungus. The evidence for RIP is only found in transposon sequences in the Aspergillus and Penicillium. A really interesting aspect of this discovery is RIP is thought to only occur during sexual stage, but a sexual state has never been observed for these fungi. [...]
By Jason Stajich, on February 17th, 2008
What delineates species boundaries in fungi? Much work has been done on biological and phylogenetic species concepts in fungi. Some concepts are reviewed in Taylor et al 2006 and in Taylor et al 2000, and applications can be seen in several pathogens such as Paraccocidiodies, Coccidioides, and the model filamentous (non-pathogenic) fungus Neurospora
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By Jason Stajich, on February 5th, 2008
Dettman, Anderson, and Kohn recently published a paper in BMC Evolutionary Biology on reproductive experimental evolution in two Neurospora crassa populations evolved under different selective conditions. This is a great study that complements work published last year in Nature on experimental evolution in Saccharomyces cerevisiae populations. Neurospora populations were evolved under high salt and low temperature and were started from either high diversity (interspecific crosses, N. crassa vs N. intermedia) or low diversity (intraspecific cross, two N. crassa isolates D143 (Louisiana, USA)and D69 (Ivory Coast)) as described in Figure 1. The experimentally evolved populations were then tested for asexual and sexual fitness (they were taken through complete meiotic cycle throughout the experiment to avoid insure there was selection on the sexual reproduction pathway.
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