The Broad Institute has made available the Schizosaccharomyces octosporus genome sequence producing another model system (S.pombe) with several related species for comparative genomics. I believeS. octosporus genome was entirely sequenced with 454 technology. The other genome sequences in the Taphrina clade include the S. japonicus genome. S. octosporus is pretty interesting as it grows filamentously and is 8-spored unlike S. pombe. The origin of this filamentous growth would be quite important to understand how reversions to simpler fission yeast forms form and whether this is loss of whole gene families or remodeling of gene networks.
There is also some preliminary (old) sequence from Pneumocystis (although it is hard to track down that sequence, a paper from 2006 says there is draft sequence but none shows up in GenBank).
I’m including a recapping as many of the talks as I remember. There were 6 concurrent sessions each afternoon so you have to miss a lot of talks. The conference was bursting at the seams as it was- at least 140 people had to be turned away beyond the 750 who attended.
If there was any theme in the conference it was “Hey we are all using these genome sequences we’ve been talking about getting”. I only found the overview talks that solely describe the genome solely a little dry as compared to those more focused on particular questions. I guess my genome palate is becoming refined.
A paper by Martin Aslett and Val Wood indicate that the fission yeast community is approaching 100% coverage of a GO annotation for every gene in the S. pombe genome. Only Ashbya gossypii has a smaller genome in the fungi (see a recent paper on Ashbya annotation database) and doesn’t yet have complete GO coverage. This is quite remarkable and a great dataset for studies in S. pombe and all fungi.
My quick predictions of genes a closely related species, S. japonicus, has more than twice as many genes as S. pombe (but be over-prediction by ab initio predictors). Taken in comparison to many other fungi, S. pombe represents a streamlined and reduced genome which probably occured indepdently from reduction in the Hemiascomycetes.